Is it possible topical Dutasteride is worsening hair loss?

Question

11 years ago I was diagnosed with AGA (26 yrs old). Tried finsterid but had awful side ef, so I stop. Loss has been focused on temples. 1.5years ago started minoxidil topical & oral (first 2mg, now 4mg) which worked OK. To boost response doctor prescribed to keep oral and change to minox + Dutasteride topical. But 4 months later I have been enduring massive shedding, losing density and hairs falling are miniaturized as never before. Is dut making things worse? Should I go back to only minox?

Jeff Rapaport, MD · Answer

When starting dutasteride topical treatment, some users may experience initial shedding, which is a temporary increase in hair loss before seeing regrowth. This shedding occurs because the hair follicles enter a new growth cycle, pushing out old hairs to make room for new ones. It's a common response to many hair loss treatments and often indicates that the medication is working to stimulate hair growth. However, if shedding persists for an extended period or is excessive, it's advisable to consult a hair expert to ensure proper management.
Jeff Rapaport MD FAAD 
Realself Hall of Fame 
Castle Connolly Top Doctor

Matt Tahsini, MD · Answer

Hello and thank you for your question. You may experience hair loss initially which shows the medication is working. However, this is just temporary and if it persists over along period of time you should see your doctor. Bests of luck to you.

Dr. T

Dr. T

Is it possible topical Dutasteride is worsening hair loss?

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