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In general, in persons without any particular active skin issues, home microneedling with 0.5mm needles is generally safe. However, this kind of gentle microneedling would typically be of little to no value for treating most wrinkles, folds and scars. I have been performing in-office, manual microneedling for over 23 years. (Note: I have said manual microneedling; there is no need for the added expense and risks of RF microneedling). Performed using local anesthetic, employing 1.5-2-0mm needles (depending upon the problem(s) being treated), and accompanied by the application of appropriate to problems Rx strength medications, this kind of microneedling when performed to the depth of creating numerous small punctate sites of bleeding, can be used to enhance the penetration of the medications and can likewise stimulate new collagen and elastic fiber production to really treat various kinds of aesthetic skin problems. Home use microneedling, on the other hand, is more busy work than true therapy. You would be wise to consult with a board certified cosmetic dermatologist who can help to determine whether your problem(s) are even best treated by appropriate professional mcroneedling or require other treatments instead of in addition. Hope this helps and best of luck.