Thank you for your question. Breast reduction surgery tends to be one of the most patient pleasing operations we perform. By removing “excess” breast tissue, adipose tissue, and breast skin this operation reduces and lifts the breasts to a higher position on the chest wall. By doing so, patients often find improvement in neck, back, and shoulder discomfort and find it easier to form their activities of daily living and exercise. Timing of the operation will depend on the patient's life circumstances. In general (ideally), it is best to do this procedure ( like all other elective body contouring the stages, when patients have reached their long-term stable weights. Losing weight prior to the procedure will improve the safety of the procedure and minimize the need for further surgery ( in the event of weight gain/loss after the breast reduction procedure). Keep in mind, that some of the complications that may occur when patients undergo surgery while overweight, can be very serious. On the other hand, patients with very large breasts have a difficult time exercising to their full potential; for some of these patients, breast reduction surgery (after careful consideration of potential risks/compliations is an option. In my practice, I individualize these types of decisions, "case-by-case". Best wishes as you work towards your goals and for an outcome that you will be very pleased with.