Should I use Epiduo with Accutane?

Question

Hello, I just started Accutane 1 weeks ago. Prior to that, I was on doxycycline, Acanya, and Epiduo for the past 10 months. Currently, I have more acne that I have had in the past 8 months. I believe it is because my skin has no epiduo and acanya. My face is slightly dry right now. I know i should not use the meds with accutane so the doc can gage how much mgs he should give me. (currently on 80mg a day, weigh 180lbs) What is so wrong with using epiduo with accutane? Dry skin isn't an issue 4me.

Payman Kosari, MD, FAAD · Answer

I would recommend against the use of epiduo while you're on isotretinoin (Accutane).  Accutane is all you will need to clear your acne.  Epiduo contains two ingredients, benzoyle peroxide and adapalene.  By itself, this topical can cause dryness and irritation.  As your body accumulates more of Accutane, dryness will become and issue and epiduo will compound the whole process.  Best, Dr. Kosari.

Teresa Mann, MD · Answer

Hello, Please allow the Accutane time to work and help treat your acne.  Be patient and be sure to cleanse your face with a mild cleanser and moisturize at least twice daily. Epiduo will only contribute to extra drying and irritate your skin.  I advise against the use of Epiduo while using Accutane.  Regards.

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