You should in general be okay at 6 weeks (check with your PS to be sure).But you raise many important concerns. Long flights, as well as other activities that are characterized by prolonged immobility, are increasingly known to be associated with blood clot formation in the lower legs. (The same thing can happen with general anesthesia more so than with intravenous sedation since it - GA - is a vasodilator and more likely to cause blood to pool in the veins of the lower legs.) Even aside from the peri-operative period, the tendency to get on a long flight, have a drink or two (which dehydrates), go to sleep for many hours and remain immobile, with the legs bent at the knees - is a setup for blood clot formation (also called deep vein thrombosis) and, at its extreme, pulmonary emboli.The risks can be abated by making sure that you drink lots of water, get up and move around (drinking lots of water will ensure that you have to get up!), do some stretching or motion exercises in the aisles (that's part of what those people are doing) and, generally, maintain movement.At 6 weeks you should be largely back to normal - but really not completely. It takes up to 6 months to see the final results of a lipo, which means that before then you still have at least some swelling. For that reason, I'd suggest that you be that much more vigilant and pro-active during your flight.I hope that this helps and good luck,Dr. Alan EnglerMember of #RealSelf100