Juvederm Side Effects

I'm thinking of having Juvederm for deep wrinkles between brows. Are there any side effects?

Doctor Answers 25

Juvederm, Are There Any Possible Side Effects?

Hi Cons,

As with any medical procedure there are risks and complications involved in the injection of Juvederm between the brows.

I have seen and heard of one patient who has an immediate allergic reaction to hyaluronic acid products (both Juvederm and Restylane). There have been reported cases of skin necrosis (dead skin) from injecting the product directly into a blood vessel. Along the same lines, there have been reported cases of blindness from injecting into the orbit.

Best to choose your injecting physician most carefully. Good luck and be well.

Dr. P

Encino Facial Plastic Surgeon
5.0 out of 5 stars 29 reviews

What are the side effects of Juvederm in the Glabella area.

 Besides the typical, needle based therapy, of bruising and swelling...injecting any filler like Restylane, Juvederm etc. in the Glabellar area has the risk of skin necrosis of the forehead.  When any thick material is injected in the glabella, it has the possibilty of collapsing the vein that caused skin necrosis of the forehead.  This has been well documented and IMHO this is an absolute contraindication for using any fillers in this area.  Botox or Dysport will soften unwanted lines and wrinkles, save the fillers for the face.

Francis R. Palmer, III, MD
Beverly Hills Facial Plastic Surgeon
4.5 out of 5 stars 14 reviews

Botox is primary treatment of "11 lines" but filler can be beneficial

Botox to weaken the corrugator muscles will give you the most benefit with regard to reducing your "11s." If you still have a residual wrinkle this is likely imprinted on the skin and can be improved with Restylane or Juvederm. This can be difficult to treat without causing a bumpy contour or revealing the filler product so consult with an experienced injector before pursuing filler in the area between the brows.

Stephen Weber MD, FACS

Stephen Weber, MD, FACS
Denver Facial Plastic Surgeon
5.0 out of 5 stars 81 reviews

Juvederm side effects

Consider injectables implants and not medicines and you will approach them differently when considering getting filler.  Ask your injector if they know the side effects, including how to handle complications such as necrosis, loss of vision, in addition to bruising, swelling, and erythema.  

Juvederm is risky between the eyes

There have been many people successfully treated with Juvederm or Restylane between the eyes; That being said; this is a particularly risky area with reports of skin necrosis of the forehead and even blindness because some of the product inadvertently entered an artery that communicates with blood flow to the eye; It is far better to treat this area with Botox to relax the muscles that are making the frown lines. If you keep your Botox up without letting it completely wear off between sessions (injections every 3-4 months) eventually the skin starts to recover and the lines get better. Other procedures such as some laser treatments in conjunction with Botox will also help improve those lines.  Occasionally fillers are needed for the best result and in that case, please go to only an expert and hopefully they use a blunt tip canula which makes injections safer.
I hope this helps!
Dr. Quenby Erickson

Juvederm for 11s

Thanks for this question.

The 11s ( medial brow ) are best treated with Botox. This is easily preformed with very minimal complications especially if you don't have any eyelid or eyebrow issues.

Juvederm can be injected, by an experienced person in small amounts in the 11s. This is a highly expert indication, as there are reports of loosing some skin in that area and thus getting a scar.

I really recommend trying the Botox first.

Juvederm fills indention, with minimum side effects!

The first line of defense for wrinkles between the brows is typically Botox, this stops the muscles that cause the wrinkle from contracting.If your wrinkles are deeper and present even when your muscles are at rest, then Juvederm would be the best answer (we call these static wrinkles). The Juvederm fills in the indention to smooth the area out. Juvederm really is a very safe product. Most of the issues associated with Juvederm revolve around injection site issues, and many are short lived. Most patients experience swelling and some degree of redness and discomfort at the injection site.Bleeding and bruising can also occur, but are much less likely if you avoid blood thinning medicines for 2 weeks prior to the injection (Aspirin, Motrin, Aleve, Ibuprofen). Typically injected areas are a little firm at first, but this usually softens over time. Itching or discomfort at the site also occur in rare instances. Major complications or allergic reactions to Juvederm are also extremely rare. These kinds of side effects can happen with any injectable fillers and are not more common with Juvederm than with any other filler.

Side Effects of Haluronic Acid Fillers

Fillers in the glabella can have rare but serious complications such as tissue loss and embolization.  It is very important to be aware of these potential complications.  Make sure your fillers is being done by a Board Certified Plastic Surgeon or Dermatologist with a proven record.  Many physician extenders are now doing fillers and oftentimes the procedure is being done outside of a physician office.

John Burns, MD
Dallas Plastic Surgeon
4.5 out of 5 stars 19 reviews

Common Side Effects: Bruising and Swelling

It’s not unusual for patients with deeply etched vertical glabeller frown lines to require dermal fillers in addition to Botox. When this scenario arises, Juvederm can provide excellent clinical results. Although rare, side effects occasionally occur following this type of treatment.
The most common complications seen following this procedure include bruising and swelling.These typically resolve with the passage of time. Rarely patients have unsatisfactory aesthetic results which require additional filler or in some cases reversal with hyaluronidase. In rare cases, skin loss from pressure necrosis or intravascular injection may occur.
If you’re concerned about the results from Juvederm treatments, it’s important to discuss this issue with your plastic surgeon. Your surgeon should be able to address your concerns.

Juvederm Side Effects

When injected correctly, filler between the brow can have fabulous results. However, if injected incorrectly, it can have potentially serious adverse effects.The most important thing to understand when it comes to having your face injected is to go to an experienced physician injector that not only understands how to treat the face, but also can treat the possible side effects. While the most common side effects are mild -- redness, swelling and/or bruising at the injection site. In addition, a very small percentage of patients may develop a hypersensitivity reaction resulting in prolonged red, tender or swollen areas. The most serious possible effect is skin necrosis (sloughing) and even very rarely, blindness.For deep wrinkles between the brow, one may also want to consider a combination treatment of a filler and a neuromodulator such as Botox for a synergistic effect to both fill and relax the area for a natural, youthful appearance.

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.