Juvederm Side Effects - Common Complications and Risks
Juvederm: Q&A
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Juvederm Side Effects

I'm thinking of having Juvederm for deep wrinkles between brows. Are there any side effects?

13 Doctor Answers | Asked by conservative2 in Rhode Island
+3

Juvederm, Are There Any Possible Side Effects?

Hi Cons, As with any medical procedure there are risks and complications involved in the injection of Juvederm between the brows. I have seen and heard of one patient who has an immediate allergic reaction to hyaluronic acid products (both Juvederm and Restylane). There have been reported cases of skin necrosis (dead skin) from injecting the product directly into a blood vessel. Along the same lines, there have been reported cases of blindness from injecting into the orbit. Best to... more
+2

What are the side effects of Juvederm in the Glabella area.

Besides the typical, needle based therapy, of bruising and swelling...injecting any filler like Restylane, Juvederm etc. in the Glabellar area has the risk of skin necrosis of the forehead. When any thick material is injected in the glabella, it has the possibilty of collapsing the vein that caused skin necrosis of the forehead. This has been well documented and IMHO this is an absolute contraindication for using any fillers in this area. Botox or Dysport will soften... more
+2

Botox is primary treatment of "11 lines" but filler can be beneficial

Botox to weaken the corrugator muscles will give you the most benefit with regard to reducing your "11s." If you still have a residual wrinkle this is likely imprinted on the skin and can be improved with Restylane or Juvederm. This can be difficult to treat without causing a bumpy contour or revealing the filler product so consult with an experienced injector before pursuing filler in the area between the brows.

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+1

Possible Juvederm Side Effects

Anytime you pierce the skin you run the risk of certain side effects including infection, redness, swelling, bruising, bleeding, an allergic reaction, etc. It is very important to find a reputable and experience injector that is using quality products like Juvederm, Restlyane and Perlane to avoid the risk of side effects. You may also want to consider Botox or Dysport in the glabellar area. Neurotoxins are very effective in eliminating lines between... more
+1

Juvederm for frown lines

Botox is the most commonly performed cosmetic treatment in the U.S. largely because of its great success at reducting frown lines between the brows.  For very deep lines there, however, it takes months if not years to significantly reduce the depth of a furrow.  For patients with deeper lines I follow Botox treatment 2 weeks later with a filler such as Juvederm or Restylane.  I find that the filler lasts a very long time in this area when the Botox is on board, usually about 1... more
+1

Juvederm for frown lines won't last long!

Frown lines (the 1, 11, or 111 wrinkles between our brows) are causes by activity of the corrugator supercilii muscles, which are facial muscles of expression. Botox or Dysport are neurotransmitter blockers that paralyze these muscles. One of these should always be used as the first method of treating these lines. This is because any filler (HA fillers like Restylane, Juvederm Ultra, Perlane, or Juvederm Ultra Plus) placed in these expression lines without first paralyzing the... more
+1

11 Lines - Juvederm vs. Botox

The wrinkles between the eyebrows also known as the 11 lines are generally best treated initially with BOTOX, Occasionally the addition of Juvederm to fill in deep wrinkles may also be of benefit. The risk of Juvederm include bruising and or possibly lumpiness. Rarely, patients can get a localized reaction. To learn more, visit our site below.
+1

Juvederm and Brows

Botox is the best agent used to soften the number 11's or lines between the brows.  Repeated botox injections will eliminate this line.  In deep lines, it may take as many as three sessions for this line to fade.   Fillers can be injected here, with some risk of necrosis of skin, in this area.  Their use should be limited in a supporting role and in select patients.
+1

Botox is the better choice

Juvederm can help wrinkles between the eyebrows, but, Botox is the treatment of choice. Swelling and bruising can ocrur. Lumps can develop from too much placement but this can be corrected.
+1

Restylane is better in this area.

Hi! We use Restylane for this area, but both fillers are very safe.  You can get bruising for a few days.  Other problems (such as bumps) are caused by bad injection technique, not by the material itself.  So go to an experienced plastic surgeon or dermatologist.
+1

Juvederm

Juvederm is a very safe product with minimal side effects. It is a natural substance called hyaluronic acid that slowly gets absorbed by your body over approximately 9 months. Some patients may get local irritation and redness as well as bruising but this usually only lasts a few days. Infection and bleeding are extremely rare. Go ahead and try it! Good luck!
+1

Side effects

Although it is a great product, Botox seems to be more appropriate for the area you have stated, also known as the 11’s. Around week two after the Botox treatment, fillers such as Juvederm may be used in addition. The side effects seem to be very minor, including minimal bruising a few days after the procedure. Otherwise it seems to be very well tolerated and a great choice! To minimize unwanted side effects choose your doctor wisely!
+1

Avoiding Juvederm side effects

Generally for wrinkles between the brows we first inject Botox. 1- 2 weeks latter we check the patient to see if the improvement is enough if not we inject Juvederm. In this area one must be very careful injecting any kind of filler. As long as small amounts are injected it is generally safe and will help the wrinkles between the brows that are present at rest
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Comments (1)

MBAgirl 4 Mar 2013
I spoke to a pharmacist at Midicis Aesthetics about Restylane and Restylane-L.The only diff is the L contains Lidocaine. The ingredients are: Hyaluronic acid is generated by Strep bacteria (Restylane contains gram positive bacterial proteins) NOTE: "Hyaluronan (also called hyaluronic acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions.[2] One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors. The average 70 kg (154 lbs) person has roughly 15 grams of hyaluronan in the body, one-third of which is turned over (degraded and synthesized) every day.[3] Hyaluronic acid is also a component of the group A streptococcal extracellular capsule,[4] and is believed to play a role in virulence.[5][6]" Wiki *The Restylane L contains saline and lidocaine. Both products have the same adverse reactions, or as Medicis calls the reaction, allergic or hypersensitivity reactions, which are nausea and vomiting and headaches, and anaphylaxis (the only reactions that they state as know and expected). So basically what we are likely reacting to is either the Lidocaine or the Strep bacteria proteins, bcuz Hyaluronic acid is found in the body. The definition of a hypersensitivy reaction, which it is specified as the nausea, headaches, vomiting, according to Medicis/Restylane is: Reaction produced by the immune system, which includes allergies AND autoimmunity. It requires a pre-sensitized (immune) state of the host - So I am guessing this means since I had nausea right away with the injection, I was exposed in the past to one of the ingredients and was allergic to it before the injection, (Bacteria or lidocaine), OR that is what they want us to think...What if it causes an autoimmune disease, like gluten causes celiac disease? Consider getting allergy & antibody testing done for the gram positive strep bacteria and maybe lidocaine. FURTHER RESEARCH: The Hyauluronic Acid is chemically modified with unknown added ingredient-CHEMICAL SENSITIVIES? "Native hyaluronan has a relatively short half-life (shown in rabbits) so various manufacturing techniques have been deployed to extend the length of the chain and stabilise the molecule for its use in medical applications. The introduction of protein based cross-links, the introduction of free-radical scavenging molecules such as sorbitol [found in fruits], and minimal stabilisation of the HA chains through chemical agents [!!!] e.g. NASHA stabilisation are all techniques that have been used. Research Due to its high biocompatibility and its common presence in the extracellular matrix of tissues, hyaluronan is gaining popularity as a biomaterial scaffold in tissue engineering research. In particular, a number of research groups have found hyaluronan's properties for tissue engineering and regenerative medicine are significantly improved with crosslinking, producing a hydrogel. This added feature allows a researcher to form a desired shape, as well as to deliver therapeutic molecules, into a host. Hyaluronan can be crosslinked by attaching thiols (trade names: Extracel, HyStem), methacrylates, [PLASTICS] and tyramines (trade name: Corgel) [Tyramine intake has also been associated with MIGRAINE] Hyaluronan can also be crosslinked directly with formaldehyde [POISON] (trade name: Hylan-A) or with divinylsulfone (trade name: Hylan-B) [SYNTHETIC RUBBER]" Wiki

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