We inform patients that there is a small risk of swelling and bruising after Restylane injections to the lips (a risk with any injection). Immediate ice application afterwards, Sineech, avoiding aspirin, Nonsteroidal anti-inflammatory medications, and vitamin E are all measures that can reduce the risk. If a patient has an important function soon, it may be more prudent to wait until after the event.
Rarely, some female patients will get more swelling than usual after Restylane injection to the lips. A high dose burst and taper of Prednisone 60 mg will rapidly decrease the swelling. Also, it helps to be active and move about. Staying in bed will not speed up the resolution of edema. Fortunately, most patients we inject recover quickly.


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