Nasolabial furrows often require several treatments

S. Randolph Waldman, MD answers: Restylane effects gone 2 weeks after the procedure

I had 1 syringe of Restylane injected into my left nasolabial fold about 3 weeks ago. I was immediately impressed with the results. However, after about 2 weeks, the wrinkle was fully evident again. Did the doctor do something wrong, or did my body reject it? What happened? I don't have that kind of money to waste. Thanks.


S. Randolph Waldman, MD
7 months ago

One syringe of Restylane may not be nearly enough for the correction of deep naso-labial furrows. It sounds as if your early satisfaction may have also been due to the immediate post-injection edema that is often present in the first week or so. Deep nasolabial furrows may require multiple treatments over several weeks, and we prefer Perlane, Juvederm Ultra Plus, or Radiesse for this area in most cases, since they are all a bit thicker. This area can even require some type of surgical approach but this is a subject for a different thread.

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