In our experience, most people begin to experience noticeable relaxation of treated areas with 48 hours. However, the full effects are generally realized at the 2 week mark. At this point, the key muscles have responded as well as a nice softening of the fine lines/wrinkles in the skin. Whatever wrinkles/deep lines remain after 2 weeks may be addressed with cosmetic dermal fillers such as Juvederm or Restylane.



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