The progression, persistence and/or resolution of seroma would depend upon several factors -- the cause of the seroma, the timing with which it has occurred in relation to a surgical or traumatic event, the anatomic location of the seroma, the amount of movement in the area, if a foreign body is present (ex: breast implant), and the size (volume) of the seroma. Surgeons often use drains to help reduce the occurrence of a seroma post-operatively. Drains help reduce seroma formation, but do not eliminate it; although uncommon, seromas may still form after drain removal. Small volume seromas may be more likely to resolve spontaneously compared with larger volume fluid collections. Seromas after liposuction are uncommon. Larger volume fluid collections that occur following liposuction, gynecomastia excision, and tummy tuck will likely require aspiration; and poor compression and movement of tissue layers may aggravate the persistence of a seroma. Very small seromas following breast augmentation are likely to resolve spontaneously. However, larger volume fluid collections (and especially hematomas) following breast augmentation will require treatment to reduce the risk of capsular contracture. If you have a fluid collection that you are concerned about, it is best to bring it to the attention of your doctor. He or she may elect to perform serial aspirations in the office every couple days to achieve proper healing. Best wishes.