Xeomin Potency After Mixing?

Question

How long will xeomin remain potent after mixing it. I know that botox and dysport will still be effective after 2 weeks. Is it the same with Xeomin

Raffy Karamanoukian, MD, FACS · Answer

Our office prefers to use Xeomin very quickly after constitution to maintain potency. It is not common to keep the medicine for two weeks after constitution in a busy practice. Raffy Karamanoukian MD FACSLos Angeles

Kristin J. Tarbet, MD, FACS · Answer

I don't think there is a data based answer to this, However we don't let our Xeomin sit for more than a few days.

Harry Goldin, MD · Answer

We go through our Xeomin bottles, so the material does not sit for more than a week or two.  I would start worrying about the material after 1 month, but we have not reached that amount of time.

Benjamin Barankin, MD, FRCPC · Answer

While we prefer to use all neurotoxins like Botox, Dysport or Xeomin in the same day that it is mixed, in reality if a practice is not doing enough neurotoxins, then they'll end up using older stock. That said, with all the neurotoxins, using them within 2 weeks should not be any problem as far as potency or duration. ~ Dr. Benjamin Barankin, Toronto Dermatology Centre

Alexandra Chambers, MD, PhD · Answer

Although reconstituted Botulotoxin remains potent (albeith with a decline with each passing day) for up to 6 weeks, it is not considered good practice to use medicine not freshly prepared. Doctors should use it on the same day and the same patient.

Alan M. Engler, MD, FACS (retired) · Answer

That's a good question but I don't know that there's an exact answer.  While studies showed that some botulinum toxin retains its effectiveness for up to six weeks, I don't generally recommend using solution that's been around for two weeks.  I prefer to use it on the day it's reconstituted and I try to schedule my appointments so that that is possible.  That may mean suggesting to patients that they bring a friend with them so that the entire bottle can be used at one time or, if necessary, we try to arrange that.As always, you (as the patient) should know how many units you're getting and how old it is.  That's the only way you can reasonably compare prices and treatments and, ultimately, the final results.I hope that this helps and good luck,Dr. E

Xeomin Potency After Mixing?

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