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Our office prefers to use Xeomin very quickly after constitution to maintain potency. It is not common to keep the medicine for two weeks after constitution in a busy practice. Raffy Karamanoukian MD FACSLos Angeles
I don't think there is a data based answer to this, However we don't let our Xeomin sit for more than a few days.
We go through our Xeomin bottles, so the material does not sit for more than a week or two. I would start worrying about the material after 1 month, but we have not reached that amount of time.
While we prefer to use all neurotoxins like Botox, Dysport or Xeomin in the same day that it is mixed, in reality if a practice is not doing enough neurotoxins, then they'll end up using older stock. That said, with all the neurotoxins, using them within 2 weeks should not be any problem as far as potency or duration. ~ Dr. Benjamin Barankin, Toronto Dermatology Centre
Although reconstituted Botulotoxin remains potent (albeith with a decline with each passing day) for up to 6 weeks, it is not considered good practice to use medicine not freshly prepared. Doctors should use it on the same day and the same patient.