I Had Xeomin 2 Days Ago (Wed Afternoon) and Am Severely SWOLLEN? (photo)

Thank you for your question.

It looks like you have lymphostasis: muscles play role in draining fluid between cells in tissues. When they suddenly 'switched off' with Botulo-toxin - this normal drainage slows down untill alternative muscle groups take up this function. Normally this phenomena seen in people who are relatively new to Botulo-toxin treatment and it lasts about for 2-3 weeks, it is normally worse the first thing in the morning and improves towards the evening when patient has been up and about.

This looks like a reaction from the injection process itself rather than to the material that was injected.  It is, of course, hard to say without an exam but there may have been some excess bleeding (always possible with an injection of any kind) or other trauma to the tissues.  A steroid (prednisone) is completely appropriate; the furosemide may not have been necessary (again, hard to say).  Either way, this should resolve over first week or so following the injection. 

I hope that this helps, and good luck,

Dr. E