Evolence is a new dermal filler made of natural collagen, that has been naturally cross-linked to mimic the natural structure of the body’s own collagen. As a result, Evolence is able to integrate and support existing collagen by adding structure, strength, and volume for a natural appearing, long lasting result. Evolence is indicated in patients with moderate to deep facial wrinkles and folds, such as nasolabial folds, along with areas that require lifting such as the corners of the mouth and lateral eyebrows. Evolence effectively works as a “thread-lift” by building three-dimensional structure and support, effectively lifting areas to a more youthful position. Injections are very comfortable, with immediate results, and last through 12 months.