Regardless of its composition (serum or blood), the collection may well lead to this area not adhering to the underlying layer without re-operation. This needs to be aspirated, drained, or surgically removed, all of which are minimal compared to what time, money, and surgery you have invested thus far.See your surgeon immediately; the longer you wait, the higher the likelihood of developing a pseudobursa, which has an even higher risk of requiring re-operation to resolve. This is not an emergency as you ahve had this collection for at least a portion of the past 3 weeks, but it IS an urgency. Call your surgeon's office first thing tomorrow and be seen ASAP. Best wishes! Dr. Tholen.