Is hyper diluted Sculptra safe to be injected in the neck?

Hello! My name is Jessica, I am a physician assistant, and one of the providers at Aesthetic Skin - Winnetka & Chicago. This is a great question. Yes, hyperdilute Sculptra is generally considered safe for use in the neck. Sculptra, which is made of poly-L-lactic acid, works differently from traditional dermal fillers—it doesn’t provide immediate volume but instead stimulates the body to produce its own collagen over time. When hyperdiluted, Sculptra is mixed to create a thinner solution that spreads more easily across broader, delicate areas like the neck. This makes it particularly useful for improving skin texture, firmness, and the appearance of crepey skin rather than adding bulk. Because the neck has thinner skin and a more complex anatomy with underlying muscles and vessels, precise injection technique and conservative dosing are crucial to minimize risks such as nodule formation or uneven texture. Most patients tolerate the treatment well and notice gradual improvement over a few months, with results that can last up to two years. I hope this helps and best of luck!

Personally, I prefer not to inject Sculptra into the neck. Sculptra needs to be placed relatively deep to minimize the risk of forming palpable nodules. However, most neck injections are performed superficially—just beneath the skin—which increases the potential risk, even when using diluted Sculptra. Typically, patients prefer skin-tightening treatments for the neck. If volume restoration is needed, I recommend fat grafting over Sculptra injections in this area.

Hello SarahGG and thank you for your question! Hyperdilute Sculptra can be safe for the neck, but only when done by someone with the right training and experience—which is why you're getting mixed answers. Some providers use it off-label to help improve loose or crepey skin by boosting collagen, and when it's properly diluted and injected at the right depth, it usually works well and safely. But the neck is a sensitive area with thinner skin, so if it's done incorrectly, it can cause lumps or other issues. Some providers avoid it because of these risks or because it's not officially approved for the neck. If you're thinking about it, choose someone who does this treatment often, can explain how they do it, and has good results to show. Best of luck!
Genie Alexander for Anna Petropoulos, MD FRCS
Center for Classic Beauty
Boston & Danvers, MA

Please do not use Sculptra in the neck. The risk of nodule formation is very high. Even higher dilutions might not protect you from this complication.
Regards
Dr. Janjua

Injecting hyper-diluted Sculptra into the neck can be a safe and effective procedure when performed by an experienced and qualified practitioner. Sculptra is a poly-L-lactic acid (PLLA) injectable that stimulates collagen production, and its use in the neck area can help improve skin texture and firmness.

Considerations for Safety:

Provider Expertise: The safety and effectiveness of Sculptra injections in the neck largely depend on the skill and experience of the provider. It is crucial to choose a board-certified dermatologist or plastic surgeon who has extensive experience with Sculptra injections, particularly in off-label areas like the neck.

Dilution and Technique: Hyper-diluting Sculptra involves mixing the product with more sterile water than usual to spread it more evenly across larger areas, such as the neck. This technique can reduce the risk of nodule formation and ensure a smoother result. Proper technique in injection depth and placement is essential to avoid complications.

Individual Assessment: Every patient is different, and a thorough assessment is necessary to determine if this treatment is suitable. Factors such as skin thickness, elasticity, and overall health should be considered.

Potential Risks: As with any injectable treatment, there are potential risks, including bruising, swelling, and, rarely, the formation of nodules or granulomas. An experienced provider can minimize these risks through proper technique and aftercare instructions.

Consultation Advice: Before proceeding, have a detailed consultation with your provider to discuss your goals, expectations, and any potential risks. This discussion should also cover the provider's experience with Sculptra in the neck area and any specific aftercare recommendations.

Ultimately, while some providers may have different opinions, the key to safety and success lies in the expertise of the practitioner and a personalized approach to your treatment plan.

The neck skin is thin and unforgiving. There is a higher risk for nodule formation in this area with Sculptra. I actually had a patient come see me a couple of weeks ago that had it done in the neck by another injector and formed a nodule. Should it occur it is difficult to resolve. I would avoid it.

Even though sculpture can be injected into the neck, I would not recommend it no matter what the dilution is. The product is supposed to be diluted in approximately 10 cc of saline. The best thing that should be injected into the neck is your own fat, but if that is not available, then Sculptra can be considered yet the person injecting it better be extremely, extremely experience. I hope this helps and good luck from Leonard Grossman MD, organic Plastic Surgery NYC