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Traditionally, salicylic acid and benzoyl peroxide are used to treat clogged pores and are the most well-known skin-clearing active ingredients. However, there are many other exfoliating acids that help to maintain clear and healthy skin, such as prescription Tretinoin, Glycolic acid, lactic acid, bromalin enzymes, etc. It is always important to reach out to your skin provider for the best recommendations for your skin type.