Can I have fillers and Botox with having Lupus?

Systemic Lupus Erythematosus is an autoimmune disease.
Both are probably safe, but Botox may not have it's full effect, as you may have or develop antibodies to the compounding proteins in the commercial preparation. This is called tachyphylaxis.
Dermal fillers are hyaluronic acid and also probably safe but you are at a higher risk of developing an adverse reaction or a granuloma. I would suggest a very low concentration of hyaluronic acid (not cross linked) or PRP.
Sincerely,
Dr. Anna Sylwestrowicz MD, FRCP(C)
Victoria, BC

Chances are pretty good that you can have both, fillers and Botox even though you have Lupus. When I see patients like yourself I generally ask them to speak to their physician who's treating them for lupus and they will provide them with the answer based on their current condition. Good luck from New York City