What % of patients lose fat around the eyes after using Latisse?

There is no research to indicate that patients lose fat around the eyes after using Latisse. Side effects (including eye lid irritation and skin discoloration) resolve after discontinuing Latisse.

You've hit on an important question with Latisse. Many people have some degree of fat loss or lid skin tightening around their eyes after using Latisse for eyelash growth.  Most find it unnoticeable or like the appearance, some decide to stop the medication, others keep going and have a little filler injected to get the look they want. The fat loss is more noticeable in older patients as they have already begun to naturally lose volume and like Cinderella, the eye changes will largely return to normal over time if Latisse is discontinued.