Undergoing arthroplasty while on Accutane (isotretinoin) requires careful consideration due to the potential effects of Accutane on wound healing and tissue repair. Here are some points to consider: Accutane and Surgery: Accutane is known to affect skin and soft tissues, potentially leading to delayed wound healing and increased risk of scarring. This is particularly important to consider when planning any surgical procedures. Consultation with Your Surgeon: It is crucial to have an open discussion with your oral surgeon about your current use of Accutane. They can assess the risks and benefits specific to your case, considering the severity of your TMJ issues and the potential impact of delaying surgery. Pain Management: If the pain from TMJ is severe and significantly impacting your quality of life, your surgeon might weigh the benefits of proceeding with surgery sooner rather than later. Discuss alternative pain management options that could help alleviate symptoms if surgery is postponed. Dermatologist's Input: Involve your dermatologist in the decision-making process. They can provide insights into any necessary adjustments to your Accutane regimen and how it might affect your surgical outcomes. Potential Alternatives: Explore non-surgical options or temporary measures that might offer relief from TMJ pain while you continue Accutane, if surgery is deemed too risky at this time. Post-Surgery Considerations: If you and your healthcare team decide to proceed with surgery, ensure that a comprehensive post-operative care plan is in place to support optimal healing, including possibly pausing Accutane use as advised by your healthcare providers. Ultimately, the decision will depend on a thorough evaluation of your specific medical circumstances, the severity of your symptoms, and the professional guidance of your healthcare providers.