Can You Use Tretinion and Hydroquinone Together Interchangably?

How can you udon both of these cream at the same time safely and correctly to achieve opitimum results

Doctor Answers 4

Tretinoin (Retin-A) and Hydroquinone together

Retin-A and Hydroqinone work well together to treat melasma.  There is a product called Tri-Luma that has both of these agents along with a topical steroid to help decrease irritation.  You don't have to worry about the optimum combination since it is a single application product (each day).  Tri-Luma is currently unavailable, but it can be compounded by a pharmacist.  Hope this helps!

Las Vegas Dermatologist
5.0 out of 5 stars 4 reviews

Tretinoin and Hydroquinone often used together

Hydroquinone is used to treat dyschromia (abnormal pigmentation). Retin A (Tretinoin) is used for acne treatment and prevention but also helps to lighten the skin and dermal thickness. Both can be used at the same time and work synergistically for pigmentation issues.

Larry S. Nichter, MD, MS, FACS
Orange County Plastic Surgeon
4.9 out of 5 stars 159 reviews

RetinA and Hydroquinone...

For optimal results I recommend using both products together in the evening before you go to bed.  RetinA will help Hydoquinone penetrate better and give you better results.

Consult your physician prior to starting these products. 

Hope this helps.


Dr. Grant Stevens        Marina PlasticSurgery Associates          Marina del Rey, CA         The Institute


Grant Stevens, MD
Los Angeles Plastic Surgeon
4.7 out of 5 stars 148 reviews

Tretinoin and hydroquinone

Tretinoin and hydroquinone are both used for fading brown pigmentation.  They are often prescribed as a mixture together with a cortisone cream for maximal results.  It is important to use sun protection to prevent repigmentation.  You should consult a board certified dermatologist to assess your skin and ensure you are using the correct products.

Martie Gidon, MD, FRCPC
Toronto Dermatologist
5.0 out of 5 stars 22 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.