How can I get the right side of my face as taut as the left side?

One side of my face is much more taut than the other. One side of my face is much more taut than the other. I used to sleep my right side, which caused a lot of acne on that side of my face. The pores are much larger on the right side and when I smile, they scrunch up causing lots of wrinkles that are really close together on my cheek, where as the other side is taught and doesn't wrinkle up when I smile. Should I use more Retin-A on the side with the looser skin? Is there something else I can do or use that is specifically targeted for tautness?