Any time you see medical recommendations, estimates of benefits, or lists of potential side effects, these are based on analyzing the reactions of large groups of people in scientific studies. Individual reactions will vary. We recommend repeating Botox after 3 to 4 months because that is the time at which most people tend to notice their results diminishing. If your muscles are very active, you may find your effects wearing off sooner. If you need more Botox, feel free to get it. It's perfectly safe to have another treatment before the 3-month mark. Please consult a board-certified dermatologist who is an experienced Botox injector so that you can be assured you are being treated correctly and with the proper strength of Botox.