Open wound after sclerotherapy. Help please! (Photo)

Stop using neosporin if you are developing a reaction to it. It may be stasis dermatitis that is confused with a reaction but nevertheless, stop using it. If there is drainage from the wound, it is likely infected and needs to be treated with oral antibiotics. It would also be wise to culture it before treatment.What you need to do is get a formal ultrasound venous Doppler examination to see if there is associated superficial vein thrombophlebitis which also needs to be addressed as well. Seek a board certified vein specialist from the 'physician locator' icon on the American College of Phlebology Website. 

This needs to be evaluated in person by a vein expert. Also, stop using Neosporin and never use it again. Many, many people are allergic to it and should not use it. You are one of them apparently. But you need to see a vascular surgeon regarding the wound. "This answer has been solicited without seeing this patient and
cannot be held as true medical advice, but only opinion. Seek in-person
treatment with a trained medical professional for appropriate care."