I can understand why you’re anxious, especially given your prior experience with filler necrosis requiring dissolution. When something like that has happened before, it’s completely reasonable to be more cautious about any new color change or unusual sensation in the area. The reassuring part is that a true filler-related infection appearing for the first time 1.5 years later is uncommon. Most infections associated with hyaluronic acid fillers occur within days to weeks after treatment, not after a year and a half. What the Discoloration Could Be Without examining you in person, the possibilities I would consider include: Post-inflammatory pigmentation from prior irritation, acne, shaving, or friction Residual vascular changes from previous filler treatment Normal shadowing or contour irregularity that becomes more noticeable as filler gradually breaks down Less commonly, a delayed inflammatory reaction to filler, which usually presents with swelling, tenderness, firmness, warmth, or nodules, not just a subtle color difference. The “Weird Sensation” When Pressing on the Jaw That symptom is actually more suggestive of a sensory nerve irritation or altered tissue sensation than of an infection. The chin and jawline contain branches of the mental nerve and other small sensory nerves, and pressure over scar tissue, prior injection sites, or tight fascial tissue can sometimes create a tingling, pulling, or electric-like sensation. A few questions that would help narrow it down are: Is the sensation tingling, numbness, burning, or shooting? Has it been present since the original filler treatment, or is it new? Do you have any persistent numbness of the lower lip or chin? Persistent numbness would deserve a more careful evaluation before any additional filler is placed. About the Doxycycline Doxycycline is unlikely to be causing a localized chin discoloration. In fact, because it has anti-inflammatory properties, it is sometimes used to help calm inflammatory skin conditions. It would not typically mask a significant filler infection. I’m Glad You’re Waiting Before Refilling Stopping nicotine is one of the best things you can do before any cosmetic procedure. Nicotine can reduce blood flow and impair healing, so giving your body at least two weeks nicotine-free is a very reasonable precaution. Should You Be Concerned About Late-Onset Inflammation? Late inflammatory reactions can occur months or even years after filler, but they usually involve one or more of the following: Swelling that comes and goes Firm lumps or nodules Redness and tenderness Symptoms that flare after an illness, dental work, vaccination, or other immune trigger If your main concern is color alone, with no swelling, pain, warmth, or palpable lump, I would place infection lower on the list. Given Your History of Prior Vascular Compromise This is the part I would take most seriously. A previous episode of suspected necrosis after filler does not necessarily mean you can never have filler again, but it does justify a very careful reassessment before repeating treatment. I would want any injector to: Review exactly what happened during the necrosis event Examine the current chin and jawline for vascular or scar-related changes Determine whether any residual filler is still present (ultrasound can sometimes be helpful in complex cases) Discuss whether the treatment plan should be modified or performed more conservatively. My Honest Impression Based on what you’ve described, I would be more suspicious of residual pigment, vascular change, or altered sensation from prior filler treatment than of an active infection. The unusual sensation when pressing on the jaw is worth evaluating, but by itself it does not strongly point toward a late filler infection. The most important thing is not to rush into refilling simply because the previous filler has faded. Since you already have both a visible color change and a new sensory concern, those issues should be clearly understood first so that any future filler treatment is done as safely as possible.