Botox etc has completely stopped working, is it possible it will ever work again?

It can be frustrating when a once-effective treatment no longer works as expected.Resistance to Botulinum toxin is possible but rare. It can happen when the body forms neutralizing antibodies against the toxin, usually after frequent high-dose treatments. However, complete non-responsiveness is uncommon.Here are some strategies to address this situation:Try a different brand or type of Botulinum toxin, as each product has a slightly different formulation.You can discuss increasing the dosage or frequency of injections with your healthcare provider, but this should be done cautiously.Taking a break from treatments may help reduce antibody levels, allowing the toxin to work again.Consider alternative aesthetic treatments like fillers, thread lifts, or laser treatments if Botulinum toxin is no longer effective.Always consult your healthcare provider before changing your treatment plan. They can offer the best advice based on your specific situation.

If neurotoxins have stopped working you may want to turn to other healthy skin treatments for improvement. Morpheus8 combines RF technology with microneedling to improve overall skin tone and texture. We also recommend using medical grade skin care products like Transform MD and wearing sunscreen every day.

Neurotoxin tolerance, specifically referring to botulinum toxin-based injections, has been a topic of discussion in recent years, and there are a few factors to consider:
Tolerance Due to Frequent Use: There is a concept known as "Botox tolerance," which suggests that over time, the effects of Botox may diminish if it is used too frequently. This may be due to the development of antibodies against the toxin. Some individuals may experience reduced effectiveness if they receive Botox injections very frequently.
Post-COVID Neurotoxin Tolerance: Some reports and studies have suggested that COVID-19 might lead to changes in the immune system and, in some cases, affect the response to botulinum toxin treatments. However, research on this topic is ongoing, and the extent of the effect remains unclear.
It's important to note that tolerance to botulinum toxins can vary from person to person. Many individuals continue to benefit from these treatments without developing tolerance or experiencing diminished effects, even with repeated use.If you have concerns about Botox tolerance, it's essential to discuss them with a qualified medical professional who administers these treatments. They can provide personalized guidance and treatment plans that take into account your unique circumstances. They can also monitor the frequency of injections to ensure that you receive the best possible results. Additionally, ongoing research is being conducted to better understand the relationship between COVID-19 and botulinum toxin treatments, so staying informed about the latest developments is advisable.
Hope that helps! ....Lena

The majority of aesthetic practices administer botulinum type A toxins. Myobloc is a botulinum toxin type B toxin and can work in patients that have stopped responding to the type A toxins. Another option is stopping neurotoxin altogether for 3 years has been successful for some patients to regain effectiveness.

It sounds like you may have had too much of the neuromodulation her at one time. Once you reaches certain threshold, with Botox it is 300 units, your body will make antibodies and will neutralize the botulinum protein so it will not work.

The active molecule of every branch of neural modulator is a small protein called the light chain. The size of this protein is small and goes below the detection level of the immune system. Once the amount of protein injected reaches a certain threshold to triggers your system to believe there is a danger and your body naturally synthesizes antibodies rendering the light chain protein useless. For scientist studying neurotoxins, they are given an inactivated protein vaccine to purposely give them antibodies to prevent poisoning.

A botulinum toxin antibody test will prove whether you have antibodies or not.