Should Spironolactone for Acne Be Stopped Before Pregnancy? If So, How Long Does It Need to Be Discontinued Before Conceiving?

Doctor Answers 3


There are no double-blind controlled studies that have been conducted on this specific topic. Based on the metabolism of the medication, I would recommend a 6 week wash out of the drug, just to be absolutely certain.

Alpharetta Dermatologic Surgeon
4.4 out of 5 stars 14 reviews

Spironolactone and Pregnancy

Absolutely stop Spironolactone before conceiving as it can cause feminization of a male fetus and may also lead to miscarriages.  It is unclear how long you need to be off the medication.  Please discuss this with your Ob/Gyn.  

Sheri G. Feldman, MD
Beverly Hills Dermatologist
5.0 out of 5 stars 1 review

Discontinue spironolactone before conception

Spironolactone is pregnancy category C.  It should not be used during pregnancy.  I recommend stopping it as soon as you decide that you are trying to conceive.

Melissa Chiang, MD, FAAD
Houston Dermatologic Surgeon
5.0 out of 5 stars 12 reviews

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