Is it normal not to see much change of a moderate acne case after 2 months of 40mg of accutane per day if you weigh 50kg?

Many people will experience worse skin when starting Accutane and this can last for up to a few months depending on how bad the acne was to begin with. This has to do with the pores underneath the skin changing and so everything has to come up and out. It will get better but it will take time. There is a good chance that you may have to be on the medication longer than 5 months. The range is between 8000-16000mg cumulative dose, so that's quite a range. "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."