If you know you respond well to BOTOX®, then there’s really very few risks for using injections to treat sweaty palms. Some people may notice pain at the injection site, but this can be alleviated with a topical numbing cream or by taking an over-the-counter pain reliever like ibuprofen before your appointment. The main side effect mentioned here, concerns over weakness in the major muscle groups of the hands, shouldn’t be an issue as long as you go to an experienced injector who is familiar with using BOTOX® for hyperhidrosis treatment. As long as you take your time to look around and find a practice you’re comfortable with, you should see great results using BOTOX® for your excessive sweating.