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I would highly recommend that you see your provider for follow-up as enough time has past to still be experiencing pain.
While the ankle does tend to be a bit more sensitive to sclerotherapy treatment, any sensitivity or soreness should have diminished after 3 weeks. As a sclerotherapy and vein expert, I recommend you see your doctor for a follow-up to ensure there is no more serious complication at play here.
The recommendation from Board Certified Phlebologists (vein specialists) like myself is to get an urgent Doppler ultrasound evaluation to make sure you don't have a deep vein clot.
I would expect that the soreness and tenderness would be gone by now. I would have the area evaluated by the doctor that did the treatment to ensure no complications, such as infection or blood clots. It may just be continued inflammation (i.e. phlebitis) as the veins respond to the treatment, but all of this is typically gone by 3 weeks. There are more nerves in the region of the foot and ankle than there are in the leg, so the risk of persistent nerve pain is higher when the ankle and foot are treated.
The most sensitive area for sclerotherapy seems to be around the ankles probably because there is only skin and bone there and not enough fat to serve as a cushion. Because of this I have found sclerotherapy to be uncomfortable in this area but I have not seen the soreness last for 3 weeks post treatment. I would be concerned that there is a reason for the continued soreness such as a clotted vein ( superficial or localized deep vein phlebitis) or skin sensitivity secondary to leakage of the sclerosing solution into the surrounding tissue. You should follow up with your treating physician.
There are several different agents used for sclerotherapy all are irritants and work by causing an inflammatory reaction to the lining of the spider vein. Most of the localized sensitivities are usually gone by 2 weeks. If it is persisting then you may want to be evaluated by your physician.
At three weeks out your swelling should be well gone. I would suggest you follow up with your treating physician for an evaluation. You might have been more sensitive to the solution used for the sclerotherapy (there are many kinds so I'm unsure what was used), but after three weeks, swelling should have resolved.
This is a lesion that should be seen and examined by a urologist. Often a scrotal ultrasound is done to ensure there are no intrascrotal/testicular abnormalities and nothing else likel varicoceles ... Seek guidance from a urologist.
Often, chest veins are isues in people who have thin, white skin as the green blue hue of the varicose veins are quite obvious. These are very effectively treated with one or more sessions of foam sclerotherapy with high succes rates. Sclerotherapy can also be used for breast veins.
These are superficial and cosmetic veins and treating them will have no untoward consequences and will NOT cause problems with arteries as you have suggested.