I know the half-life of doxycycline is slightly less than 24 hours so it should theoretically be out of your system within 5-6 days, but I am concerned because the half-life of accutane is also around 24 hours but accutane patients are prohibited from getting pregnant 1-2 months after their last accutane pill, which makes me wonder whether a similar time frame is needed between stopping doxycycline and starting accutane? (Especially regarding intracranial hypertension and liver problems).