Large hole at the end of my incision, which is raised swollen and bumpy. Is this normal? 4 wks post op breast lift. (photo)

It is not uncommon to see this in some patients.  Most important is to make sure you are not having any fever with this.  I would definitely contact your surgeon and send a photo in to them.  They will probably have you go in and have it cleaned to avoid any infections. Best of luck !

This is unfortunate but it is a relatively common occurrence after breast reduction. This is a point of increased tension in the closure and as such, it is prone to slow healing.
With some time these areas usually heal with minimal to no scarring.
Make sure you follow up closely with your plastic surgeon.

You certainly seem to be having healing issues with the right breast. Wounds will heal with time and if needed a revision of the scars can be performed. For now, you should follow up with your surgeon to make sure there is no infection, as well as instructions for taking care of the wounds.