Can weight loss result in an inverted nipple?
Doctor Answers 2
Cause on Inverted Nipples
Weight loss certainly would explain the loose skin of the breasts. The concern for nipple inversion is that one of the causes as you mentioned can be a symptom of cancer. While unlikely from the information provided, the seriousness of the consequences of delay would suggest one should go see her Physician for an evaluation and based upon that consider a mammogram to follow-up suspicions.