I suggest that patients stop using Retin-A, retinoids, etc. for a minimum of 3 days before getting an IPL treatment. You can start again the next day, but it's best to be off it for a few days because it can make you more susceptible to burning from the IPL. If you don't stop it or you forget, make sure you tell your technician because they will need to lower the settings. "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."