I Am Taking Minocyline for Perioral Dermatitis. Is It Safe to Have Botox?

Question

I am 45 years old and have been on minocyline for approximately 4 years, I would like to have Botox and wondered if this was safe? Thank you

Jerome Edelstein, MD · Answer

It should not have any effect on your Botox, however you should let your injector know about any medications you're taking before you have your treatment.

Harold J. Kaplan, MD · Answer

Hi Audrey.  No need to worry as the anitbiotic you are taking will not interfere with your Botox injections.

Make sure to let your MD know about all themedications and supplements you are taking as some can have a much higher probablility of leading to bruising.  Good luck.

Ron Shelton, MD · Answer

You should have no concerns in taking Minocycline while having Botox injections for muscle relaxation. There is no interaction between the metabolism of the Minocycline (Minocin) antibiotic and Botulinum toxin. The Botox works by acting as a competitive inhibitor of the neurotransmitter between the muscle and nerve. In other words, the Botox molecule looks similar to the normal chemical that is transmitted as a signal between the nerve and muscle which makes the muscle move. When Botox is brought into that receptor it does not transmit the signal. It acts as a dummy blocker. This will not cause any affect on the mechanism of action of Minocycline.

Monika Kiripolsky, MD · Answer

Yes, minocycline (a medication of the tetracycline class of antibiotics) is safe to be taking while having Botox injections.

	     The class of antibiotics that patients should not be taking when having Botox injections are those of the aminoglycoside class. Some of the most common (oral) aminoglycoside antibiotics are amikacin, gentamicin, tobramycin, and streptomycin.

	      It is always best to tell your doctor all of the medications that you are taking before undergoing any procedure, including Botox injections. Good luck and enjoy your Botox! MK

Deborah Sarnoff, MD · Answer

There is no problem having a Botox treatment at the same time as you are taking minocyline. The main side effect to be aware of concerning minocyline is photosensitivity -- therefore, be sure to be careful in the sun and always apply sunscreen.

Victoria W. Serralta, MD · Answer

Botox and minocycline will have no negative interaction on each other. In fact, if your perioral dermatitis tends to become worse with sweating, as some patients note, the botox may actually help slightly as it stops sweating in addition to treating wrinkles.

Lisa Kates, MD · Answer

There is no contraindication for Botox injections and Minocycline or any other form of Tetracycline.  It is very important to inform your injecting doctor of your medications.  But you are good to go.

Peter L. Kopelson, MD · Answer

Yes, it is safe to have Botox for a patient who regularly takes minocycline. However, minocycline increases the likelihood for Hyperpigmentation. While it is unlikely, Hyperpigmentation may occur at needle point of entry.

Margaret Mann, MD · Answer

Absolutely safe!  Minocycline will not interfere with your Botox treatment (they do not cross-react), so it is safe to use together.  There are other classes of antibiotics which should not be taken while having botox injections, but minocycline is not one of them.  It is always best to let you doctor know what medications you are on. 

	Best,

	Dr. Margaret Mann

Robert Kasten, MD · Answer

This is safe combination. Taking minocycline for such a long time should be reevaluated with your dermatologist, though.

I Am Taking Minocyline for Perioral Dermatitis. Is It Safe to Have Botox?

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