I've built up a resistance to Botox over the last 10 yrs, will Botox ever work for me again?

You can try to switch to another product like Dysport. It does the same thing that Botox does. Many patients can switch back and forth between the two if they are noticing a resistance. It's best to consult with a local physician. You may also need to have more units injected.Good luck!

I would considering using dysport or xeomin as an alternative to Botox. I recommend getting a formal consultation with a cosmetic dermatologist. Best, Dr. Emer.

Botox resistance occurs with number of patients but there are alternatives to Botox that can be used. As expected, those alternatives are not as popular because they cost more and there is greater discomfort after injection. I would suggest you to talk to your provider about Dysport and Myobloc. Moreover, depending where you wee getting botox injections, there are other treatments that can help you attain more permanent results and less “puffer fish” look such as limp implants or Restylane for fine lines and wrinkles. Good luck!

Hi there.  We have actually seen Botox resistance in practice.  Although Xeomin is commonly offered as an alternative, they are both Botulinum type-A toxins, which often means clients also see the same result after Xeomin injection.

The best alternative would be Myobloc which is botulinum type-B.  However, there is substantial extra cost, as well as much more discomfort with injection.  The product requires some experience to use and is offered much less often.  Make sure that your results are genuinely due to Botox resistance first and try the Dysport and Xeomin before moving up to Myobloc.  Good luck!

There is a theory that one can develop antibodies with consistent Botox use.  The theory describes this phenomenon as occurring with too small a dose, and too frequent an interval, of treatment. I have not seen this clinically in my practice; but have seen the "Wow" effect diminish in certain individuals that use Botox as the only modality to address an issue.  Without knowing much about your lifestyle habits, I cannot speak specifically to you.  Perhaps something of what I say will resonate.  The rate at which an individual ages is genetically determined and influenced by environment and lifestyle choices.  For instance: appropriate "sun savvy" regimens; a valuation of loss of volume in the area; UV damage to the skin itself; and how the entire face appears and interacts as an expressive unit should all be considered.

Lastly, even if none of the aforementioned plays a role, the placement of the Botox needs to be altered by a few millimeters from time to time.  This can be challenging in that you do not want to stray too far from the placement to achieve your optimal effect - experienced hands come into play here.