Restylane Injections - What Risks Are There for an Insulin Dependent Diabetic?

I would like to have restylane injections to my upper lip however I am diabetic. There are surely other diabetics that have had this procedure done - did they have any side affects?
Would you recommend that I go ahead with this procedure? I would love to have this done as I have unsightly wrinkles above my lip however, I am not willing to risk looking worse or it affecting my diabetes.

Doctor Answers 8

Restylane and diabetes

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Diabetics can have restylane.  It should not be a problem in most cases.  If there are any concerns, touch base with your medical doctor.

New York Plastic Surgeon
4.2 out of 5 stars 30 reviews

Diabetic patients can have Restylane

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Well controlled insulin dependent diabetes is not contraindicated for Restylane. This means you can have your procedure.  Restylane will not effect your diabetes. Some side effects for Restylane are bruising, edema, and lumps.

Restylane will not affect diabetes

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There are no known additional risks from Restylane injections even with insulin dependent diabetes as long as the diabetes is well controlled, and Restylane will not negatively impact diabetes.

Lawrence Osman, MD
Los Angeles Dermatologic Surgeon

Restylane is OK for a diabetic

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A well controlled diabetic is a fine candidate for Restylane or other dermal fillers.  There is a theoretical risk of having an infection when injected with a dermal filler and diabetics do pose a higher risk, however, the risk is still so small that I see no reason to abstain.

Louis W. Apostolakis, MD
Austin Facial Plastic Surgeon
4.8 out of 5 stars 37 reviews

Restylane use in diabetic patients

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Restylane is a effective and powerful dermal filler that can be used throughout a face. If the patient is a well-controlled diabetic, there is no additional risk in injecting Restylane to these areas.

Diabetes not a problem for Restylane

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Diabetes is not contraindicated for Restylane. This means that it is safe for diabetics to undergo the injections. The risks for Restylane injections in a diabetic are the same as they are for non diabetic patients. These risks should be discussed with your practitioner before moving forward.

Harold J. Kaplan, MD
Los Angeles Facial Plastic Surgeon
4.4 out of 5 stars 7 reviews

No contraindication for Restylane filler injection for diabetic patients

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Individual with Diabetes may be at a higher risk of skin infection, even with minimally invasive procedure such as Restylane filler injection. However, as it is, secondary infection or delayed granuloma nodule is exceedingly rare for Restylane filler injection. Make sure that you seek out a board-certified dermatologist or plastic surgeon who utilizes good antiseptic technique to clean the affected area prior to filler injection.

William Ting, MD
Bay Area Dermatologic Surgeon
4.5 out of 5 stars 14 reviews

Restylane Injections: Facial Fillers and Insulin Dependent Diabetes: Complications

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Facial fillers have become increasingly common in the United States. The risk of injections can be categorized into two phases:

  • Immediate
  • Long term

Immediate complications include edema, bruising, and local infection. These may be affected by comorbid disease and medications the patient takes.

Long term complications include nodularity, assymetry, undercorrection, and overcorrection.

Specifically, patients with diabetes do not have any specific contraindications that would prevent treatment with facial fillers.

Always note that blood thinners, such as aspirin, ibuprofen, and coumadin may increase the risk of bruising and bleeding with injectables.


Raffy Karamanoukian, MD Kare Plastic Surgery & Skin Health Clinic; Santa Monica, CA Los Angeles Plastic Surgery

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
4.8 out of 5 stars 95 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.