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When considering the use of Pluryal fillers, it's important to be aware of potential side effects, including delayed hypersensitivity reactions. While these fillers are generally well-tolerated, there have been reports of delayed hypersensitivity reactions in some patients, as with many other hyaluronic acid-based dermal fillers. These reactions can manifest days to weeks after the injection and may include symptoms such as swelling, redness, and nodules at the injection site.If you are considering Pluryal fillers or have concerns about hypersensitivity reactions, it is advisable to discuss these with your dermatologist or healthcare provider. They can provide personalized advice based on your medical history and any previous reactions you might have experienced with dermal fillers or similar products.