Low dose Accutane: does it work?

Question

I started accutane 4 months ago. I can only tolerate 10mg 5 days/week. If I take more then my hair starts to fall off like crazy. Even with 5x/week my hair is falling more then usual. After 4 months I still break out (not as bad and they clear up faster). Will it work in the end? Will it just take more time to stop my acne completly? Do you suggest en alternative dosing like 20mg 3x/week...could it be better?

Raffy Karamanoukian, MD, FACS · Answer

Accutane is a go-to medication for patients with recalcitrant cystic acne. It can reduce pore size and also reduce sebum production in your skin, making it less oily; and in turn, dryer. Accutane can be used to control acne, but patients receiving the medication should be carefully monitored. In terms of skincare, always wear an appropriate sunscreen and reduce direct sun exposure. In my patients, I recommend a good ceramide moisturizer such as Elevase whenever they are on Accutane. This will keep the skin hydrated and reduce the oiliness of the skin that is associated with oil-based moisturizers.

Best, 
Dr. Karamanoukian 
Realself100 Surgeon

Anna Chacon, MD, FAAD · Answer

Low-dose isotretinoin (Accutane) treatment has been shown to be effective in some studies. It's generally known to reduce side effects while still providing good results. However, the duration of treatment may be longer compared to higher doses, and the relapse rate can be higher.
Hair loss is a known side effect of isotretinoin, and it's important to discuss this with your dermatologist. They may suggest ways to manage this side effect or consider alternative treatments.
As for changing your dosing regimen to 20mg 3x/week, this is something you should discuss with your healthcare provider. They are in the best position to assess your condition and adjust your treatment plan accordingly.
In terms of your acne not clearing up completely, remember that isotretinoin often takes several months to show its full effects. It's not uncommon for acne to persist or even worsen in the first few months of treatment before it starts to improve.

Low dose Accutane: does it work?

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Low dose Accutane: does it work?

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Everything you need to know about Accutane

Our mission is to create a world where every investment in modern beauty is Worth It.