I have performed sclerotherapy for more than 15 years. There are a few considerations in achieving good results from this treatment. I like to use Asclera or polidocanol because it is gentle (unless the solution went outside the vein, then it will burn). The results are highly dependent on the injector. So be sure to do your research as who performs the actual treatment and if they have had complications. Most patients require 2-3 treatment sessions so don't expect the veins to be gone with one treatment. Thorough treatment will lead to better longer term results (lasting years instead of weeks or months) but results are not permanent since the treatment does not address underlying cause of these veins, mostly genetics. Darker veins have more blood flow and will bruise more. The treated veins will look worse because of the bruising, then it will fade over a few weeks or couple months (depending on the extent of bruising), and you will see final results. So I recommend planning ahead if you have special plans to show off your legs. Larger veins can get blood trapped in the vein and may form small knots at the area, they are harmless but if it's tender, you should notify the physician. I always ask patients to show me the areas that they want me to prioritize and I draw an arrow by the area so I make sure those are treated first. Certain patients skin type are at high risk for postinflammatory pigmentation, including Asian, Hispanic, African-American. Those patients will likely develop brown discoloration over the treated veins which will take several months or 1-2 years to fade, regardless of treatment method (injection or laser). So I typically offer those patients a small test treatment to make sure they are comfortable with the extent of discoloration (which will take a long time to fade) prior to doing large treatment areas. Certain medications can cause pigmentation and should be avoided during sclerotherapy treatments including minocycline, doxycycline. Compression stockings help to minimize veins from refilling and bring faster and better results. One last but most important factor would be physical inspection of the legs with patient standing to look for bulging varicose veins. Patients with bulging varicose veins often have underlying blood flow issue with the veins known as venous reflux. If the venous reflux is not treated, the surface veins treatment with sclerotherapy will be less effective or not work at all. Seek a qualified vein specialist who treats venous reflux if you have bulging ropy varicose veins. Treatment of venous reflux are mostly covered by insurance.