Is Perlane or Juvederm better for nasolabial folds? How long does each product last?

Hi Demason,
Perlane and Juviderm are both hyaluronic acid products that last for about 6 to 9 months in most patients’ nasolabial folds. Recent studies have shown that hyaluronic acid stimulates natural collagen production so that even when they wear off there is still improvement over the original fold. Other good fillers for the NLF are Radiesse, Evolence, Elevess, and likely many more to be released in the near future.
I would be very careful of "permanent" fillers as they have been associated with severe complications often times 2 to 4 years after the injections. Granulomas (scar tissue) that are extremely difficult to remove have resulted from the "permanent" fillers. Although it may seem more economical at the time, you'd be wise to avoid the cost of the multiple corrective surgeries, not to mention the facial deformities that may result from these fillers. Be well.
Dr. P

I recommend fillers to soften the nasolabial folds themselves and also lift around the mouth and cheeks to build underlying anatomical support. In our practice we combine Sculptra with other fillers "layered" on top and lasers, skin tightening treatments such as Thermage, Fractora, and Renuvion (J Plasma), thread lifting, and peels to get the most conservative, natural look. I suggest seeing a facial sculpting expert for a formal consultation. Best, Dr. Emer

I prefer Juvederm for the nasolabial folds. In most cases, the cheaper Juvederm Ultra is good enough. But with certain people with heavier smile lines, I will use the Ultra PlusThe reason why I prefer Juvederm to Perlane in this area is that I have found that it attracts more water (hydrophilic) and I need to use less product. Therefore, it can be more cost effective for my patients.In my experience, they both last 9-12 months but it is a slow degradation so lots of people come in at 6 months for a touch up.... this keeps you at 100% fill all year round.  If, for example, you needed 2 syringes the first time, 6 months later, you may only need 1... but helps you look your best without waiting for a full year to treat again. XO

For the most part, you can't go wrong with either filler.  Perlane, in my mind, is the better filler if you need a cheek or midfacelift or to use with a facelift.  Juvederm Ultra Plus, however, also does a great job if you're primarily going after nasolabial folds or lip augmentation.  Juvederm Ultra Plus can last up to a year and Perlane up to 18 months but both require a touch up at 4 months. 

Depending on whom you see you'll get different information, however, they both are very similar in duration and can last anywhere from 6 months to over a year.

Perlane is designed for deeper planes than Restylane or Juvederm but if it is injected too deep, it won't stay around to support the skin. You may need more filler and you can try Juvederm or Restylane done more superficially.

Juvéderm XC: Used to smooth out lines along the nasolabial lines (the folds or wrinkles along the sides of your nose and mouth. Results last up to six months.Perlane: Good for more severe facial wrinkles that can benefit from a deeper injection into the skin. Contains the local anesthetic lidocaine to help reduce discomfort during and after the treatment.

I prefer Juvederm to Perlane in many cases for treating the nasolabial folds because Restylane Lyft is a bit more "stiff".  However, new Restylane Defyne and Refyne address this and have the needed flexibility for the nasolabial area.  For the best cosmetic results please consult a board certified dermatologist who is an expert in facial cosmetic injections.  Best, Dr. Green

 

 

Both Juvederm and Perlane are hyaluronic acids that smooth away wrinkles, creases and folds but I prefer to use Perlane and Juvederm Ultra Plus for deep nasolabial folds.  Perlane and Juvederm Ultra Plus are made up of larger molecules that can penetrate and fill deeper areas.  You can expect Perlane and Juvederm Ultra Plus to last anywhere from 6-12 months, depending on the patient.  Juvederm is a great choice for lip augmentation, reduction of wrinkles and for contouring the face.  I hope this information helps! 

Both Perlane and Juvederm are great choices for treating the nasolabial folds.  They are both hyaluronic acids that last long, are very forgiving, and can be reversed if necessary.  Their use in different areas is largely up to the preference of the practitioner and patient.  However, there are some very important distinctions:


Juvederm  is probably better than Perlane for treating the lips as it has a silky almost liquid-like consistency.

However, this same silkiness makes Juvederm not as suitable as Perlane for under the eyes, because it has a tendency to collect fluid and cause edema under the eyes.

 Both Juvederm and Perlane are great  for non-surgical rhinoplasty.

They are both great for the nasolabial folds, although I think it's much more important to treat the cheeks primarily than to treat the nasolabial folds.  When done correctly, treating the cheeks will support the eyes, and lift the cheeks, also improving the nasolabial folds.


Perlane and Juvederm both last about a year in all, however most of my patients are seen at 6 months, when half of the effects have faded.

In summary, they are both great products doing great things!  Good luck!

I am please with the results of both Perlane and Juvederm, for examples, please click the link below.