Is Perlane or Juvederm better for nasolabial folds? How long does each product last?

For the most part, you can't go wrong with either filler.  Perlane, in my mind, is the better filler if you need a cheek or midfacelift or to use with a facelift.  Juvederm Ultra Plus, however, also does a great job if you're primarily going after nasolabial folds or lip augmentation.  Juvederm Ultra Plus can last up to a year and Perlane up to 18 months but both require a touch up at 4 months. 

Depending on whom you see you'll get different information, however, they both are very similar in duration and can last anywhere from 6 months to over a year.

Perlane is designed for deeper planes than Restylane or Juvederm but if it is injected too deep, it won't stay around to support the skin. You may need more filler and you can try Juvederm or Restylane done more superficially.