Is there anyway to dissolve Refyne and Defyne once it is injected into your face ?

Question

My Doctor injected Refyne and Defyne around my top lip now when I smile you can not see my teeth is there anyway to fix this? How long will this last in my system before it goes away ?

Michael I. Echavez, MD · Answer

Refyne and Defyne are both types of hyaluronic acid fillers.  These types of filers can be dissolved by injection of a medication known as hyaluronidase.  I would speak to the physician who treated you to discuss this possibility.

Nima Shemirani, MD · Answer

Hi @pammy52. I'm sorry you are not happy with your results. The filler call be dissolved with Hyaluronidase. Best of luck, Dr. Nima!

Hooman Khorasani, MD · Answer

Thank you for the question. Yes, the good news is that these fillers can be depolymerized (reversed or dissolved) with hyaluronidase.
As always, an in-person consultation with a board certified dermatologist with cosmetic training is the best way to assess your needs and provide medical advice.

James R. Gordon, MD, FACS, FAAO · Answer

Thank you for sharing your question. Yes, the fillers you mention ( Restylane products ) can be dissolved with hyaluronidase. Speak with your treating physician. Good luck,

Jonathan Kulbersh, MD · Answer

Yes, if you're unhappy with your final results, you can have the filler reversed with hyaluronidase. It can take a series of treatments to dissolve fillers. Hope this helps.

Monika Soni, MD · Answer

Thank you for your question. Both Refyne and Defyne are hyaluronic acid fillers that can be dissolved with an enzyme known as hyaluronidase if unhappy with your results. However, it can take several treatments to fully dissolve your filler. I recommend having a follow up with your injector for an evaluation and to discuss your concerns. Best of Luck!

Hardik Doshi, MD, FACS · Answer

Pammy, Refyne/Defyne are fillers comprised of hyaluronic acid (HA) and can be dissolved using hyaluronidase, which breaks down the filler so that it can be cleared away by the body. Since Refyne/Defyne has greater cross linking, it may be take a bit more hyaluronidase, but can easily be dissolved. All the best!

Darryl J. Blinski, MD · Answer

OFCOURSE!!! The dissolver injection product is - Hyaluronidase. But most injectors under treat with this dissolver. I recommend at least 10 sessions @ $500/session to obtain best outcomes.

Flawless Med Spa - Bryant · Answer

Restylane Refyne and Defyne are hyaluronic acid dermal fillers. These particular types of dermal fillers can be dissolved by using hyaluronidase. It quickly breaks down the filler that was injected, however the amount is dependent upon how much dermal filler was injected and where. I would return to the provider that injected your filler and discuss what is wrong and what you do not like so that everyone can make an informed decision. Hope this helps. 
Best of Luck!

Is there anyway to dissolve Refyne and Defyne once it is injected into your face ?

Answers (9)

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