Hello,This is not a normal or expected reaction to TriLuma. TriLuma retinoid within the product which may be what you are reacting so strongly to. We suggest that you contact the physician that prescribed this to have them address the issue and calm down your skin. If you were prescribed this for upper lip brown discoloration, you may want to consider our product of hydroquinone. The difference is - we do not add retinoids to our compounded product. This makes it far more tolerable for patients and the cost is generally less than TriLuma and, in our opinion, much more effective.Please see the link below. Please also practice very gentle skin care to this area, stop the TriLuma and contact your MD, diligent sunscreen use.