How long should you wait to start PRP for skin rehabilitation after damage from non-ablative nd:YAG lasers?

You’re asking an excellent question — timing is indeed crucial when using PRP (Platelet-Rich Plasma) for post-laser or thermal injury recovery.

If the skin shows acute inflammation (redness, sensitivity, peeling), it’s best to allow at least 4–6 weeks for natural recovery before applying PRP.
During this time, the body’s own repair mechanisms are actively producing growth factors and collagen — and introducing PRP too early may overstimulate inflammation rather than enhance healing.

However, if the laser damage has already stabilized (no open wounds, no active irritation), PRP can be beneficial even months later. Its regenerative properties — especially via VEGF, PDGF, and TGF-β — support collagen remodeling, vascular repair, and texture improvement, regardless of when the injury occurred.

In summary:

For fresh damage → wait 4–6 weeks.

For chronic redness or scarring → PRP can be started anytime once the skin is stable.

So yes, PRP remains effective even months post-laser, and patience in early healing improves long-term results.

Dr. Arslan Musbeh
Hair Transplant Surgeon – Founder of Hairmedico
17+ years of experience in FUE, Sapphire FUE, and DHI

This answer has been approved by Dr. Arslan Musbeh. It is not a medical advice.