MesoBotox does not ordinarily refer to a specific product, but rather to a technique for injecting Botox. I have been injecting Botox (also Dysport and Xeomin) for aesthetic reasons for over twenty-four years. These injectables work well for treating dynamic wrinkles and folds, such as the scowl lines between the eyebrows, worry lines along the forehead, and crow's feet to the sides of the eyes. Neuromodulators work by diminishing the activity of the underlying muscles of expression in these areas. Over injected or injected in too high concentrations, these agents can immobilize the muscles of facial expression entirely leading to a totally unnatural and undesirable "frozen" look. Injected properly, however, the ability to emote can be preserved while diminishing the appearance of excessive dynamic wrinkling.MesoBotox, by contrast, is the injection of more dilute concentrations of Botox (as well as the other neuromodulators) superficially, usually in the form of multiple droplets, throughout a particular area, such as the lower cheeks (where skin crinkling is present) in order to diminish the contribution of more superficial muscles to the formation of this kind of crinkling. It is also used for diminishing sweating, shrinking pores, and decrease oil gland secretion. I have been using this technique for years. However, I have found that it is far more effective for crinkles and crepey skin when combined with the superficial injection of a filler into the overlying fine and etched-in lines. Since MesoBotox injections are typically performed in areas such as the mid and lower cheek regions, it should not be performed by novice injectors accustomed to treating eleven lines. Seek consultation with a board certified aesthetic physician with extensive expertise and experience in the advanced uses of neuromodulators.