Hi. Treating wrinkles around the knee can be difficult as there are many factors causing the wrinkling. The skin is folding due to muscle movement and you may have laxity along with wrinkles due to age and sun exposure. The best option on the market is to use Thermage which is procedure utilizing radio frequency heat placed deep in the dermis to stimulate collagen production and this will improve the appearance of the area. Thermage has no downtime and is performed on a yearly or bi yearly basis to maintain collagen and elastic in the skin. However, I would not expect jaw dropping results as the results will be mild to moderate. I hope this information was helpful.