Would 1 syringe of juvederm make a difference to my nasolabial folds?

No one syringe will not help your folds.  You need full facial contouring with volumization and line filling. I suggest you see an expert for an evaluation of your overall facial structure and what is best for large volume and wrinkle improvement.  Best, Dr. Emer.

Certainly a consultation would be best so that your physician can perform a proper examination however, based on the photos submitted, 1 syringe may not be enough to to give you the result you would like since your nasolabial fold seems fairly deep. Be sure to see a board certified plastic surgeon for this procedure. Hope this helps. James Lee

Your fold is pretty deep.  One syringe of filler will soften this a little, but there will not be a dramatic difference.  will most likely want to do at least 2. 

I think you may need more than 1 syringe for full correction.  Please seek consultation with a qualified professional. Good luck!

Hello, and thanks for your question. I think you are an excellent candidate for fillers. For patients of mine with similar patterns of volume loss, I like to use a thicker, more volumizing hyaluronic acid filler such as Voluma in the cheeks. This tends to soften some of the lines lower on your face. You'd also likely benefit from some Juvederm or Restylane injected directly into your nasolabial folds (i.e., "smile lines"), and possibly your marionette lines as well. However, I'd caution against the temptation to have only these lines filled, as you are noticing them mainly as a result of global volume loss, which happens to all of us as we age. To maximize the likelihood of a favorable outcome, I recommend that you only get treated by a well-trained and experienced dermatologist or plastic surgeon. Regardless of what you have done, you will likely need more than 1 syringe.Hope this opinion is helpful to you. Best of luck, Dr. Frucht.