The skin will be quite fragile following an IPL treatment. Without knowing too much about your home microdermabrasion and its contents, it is generally advised that patients avoid using any products that contain active ingredients such as acids for at least 3 days before and after treatment. Microdermabrasion is typically quite an aggressive exfoliating treatment and would have a very abrasive, harsh effect on your freshly treated skin. I discourage my patients from having treatments for at least 2 weeks following an IPL to avoid skin injury. A light exfoliation treatment is beneficial following an IPL to rid the skin of the unwanted particles that come to the surface following treatment. In fact a really great treatment plan is to alternate the IPL and an exfoliation treatment such as dermaplaning or glycolic peel, with the proper healing time between each treatment, usually at 2-3 week intervals to avoid skin damage. Of course, I cannot stress enough the importance of using a great quality SPF of at least 30 daily but it’s especially important following a skin care treatment. A thorough skin analysis with a qualified dermatologist or skin care aesthetician is advised to develop an appropriate skin care treatment plan that will address your specific needs. Have fun with your skin care!