Foam injected on Shin, Calf, behind knee, inner thigh. I became flushed due to a reaction and was given an IV w Benadryl. It resolved quickly and I went home. post 12 weeks and now the veins are itchy, tender, skin is red and areas feel inflamed. Can the foam have been trapped in the veins and now that the veins are breaking down the foam is released into my leg causing a reaction? I can't find anything about a reaction like this online. I hope you can help.