Is it OK to use a topical erythromycin ophthalmic ointment .5% before and after Botox?

I think it would be fine to use a topical erythromycin ointment before and after a Botox treatment.  There should be no interaction.  

Thank you for your question. Using a topical erythromycin should not affect your Botox treatment. For more information, please make sure you get a in person consultation from a board-certified dermatologist. 

Thank you for your question. Topical Erythromycin ointment will not interfere with the effectiveness of your Botox and should be safe for you to use. You are correct that some antibiotics, when taken by mouth, can alter Botox effectiveness and should not be combined with Botox. These antibiotics belong to the "Aminoglycoside" group and are thought to increase the strength of Botox, which may cause unintended side effects. Examples of antibiotics from this group include amakacin, neomycin, streptomycin, tobramycin, gentamicin. For our patients that are taking these medications, we recommend finishing the course of antibiotics before having Botox. 

There's no harm in using your Erythromycin ointment for your eyelid around the time of your planned Botox treatment. 

There should be no contraindication between erythromycin ointment and Botox Administration before or after. You should give this a little time but if it doesn't resolve I would definitely see an opthamologist for your condition. Good luck from New York City