What are the chances of developing keloids after two syringes of Sculptra?

Keloids develop in skin after injury to the skin layers.  I have never seen or heard of a keloid developing from small needle sticks.  Two vials of sculptra is a routine injection amount.  

Hello and thanks for your question. 
Firstly, I’m sorry this wasn’t elucidated further in your history and consultation. Rest assured, I would say the risk of keloid formation is minimal. 
Now, we have to distinguish between keloids and the unique risk with any filler but especially biostimulators like Sculptra - nodules and/ or granulomas. Nodules can form due to an accumulation or bunching of product. Often small and can be felt, are palpable, but usually not visible to others. I would not treat those and would counsel that they are collagen, the desired result. Granulomas are often a delayed response and are an exaggerated autoimmune response. Still rare but might require surgical excision. 
Similarly, keloids which you are prone to are an exaggerated response in scarification. Since the stimulus, a needle poke is much less, I would not expect this to happen, but keloids may occur even after ear piercing. The needle gauge to pierce is much larger than that for Sculptra injection. 20 compared to usual 25. 
So, this is similar to getting blood draws and I would expect little chance of keloid formation.  
I am unaware of any specific risk in the setting of Crohn’s disease.
Hope this comforts you.
Dr. Jeffrey P. Olson

The answer is that you are at low risk. I perform this dermal filler regularly in patients with hypertrophic scars and keloids, and if used in special dilutions, the risk is even lower. All other questions answered by Dr Olsen in a comprehensive manner. All the best, Dr Davin Lim. Brisbane. Australia.